Tại sao rifampicin được dùng làm thuốc đặc trị lao?
(SK&ĐS) - Rifampicin là thuốc đặc trị lao nhưng thường được người dân gọi nôm na là "thuốc đỏ" vì bột thuốc có màu đỏ. Nó được lạm dụng khá nhiều để dùng làm thuốc bôi ngoài, rắc vào vết thương hở khiến cho tình trạng kháng thuốc có nguy cơ tăng lên. Nhiều người vẫn còn thói quen rắc bột rifampicin lên vết thương.
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